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The more D S tends towards 2, the more the analyzed vascular configuration tends to fill a 2-D space and the greater its geometrical complexity.
This permits vascular configuration to be related to oxygen availability and allows the hypoxic marker intensities to be quantitated in situ.
Compared to conventional immunohistochemistry, this method is simpler, faster and provides a more comprehensive view of the vascular configuration within the tumour tissue.
Previous studies have speculated that differences in vascular configuration between VEGF121 and VEGF165 may be related to variations in heparin binding, isoform size, or diffusivity (Guo et al, 2001; Yu et al, 2002).
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Systematic cellular and vascular configurations are essential for understanding fundamental brain anatomy and metabolism.
This method's usefulness is due to flexibility in the choice of materials and vascular configurations.
All patients were investigated using US and colour Doppler ultrasonography (CDU), which enabled the presence of testicular lesions to be confirmed, their largest diameters to be calculated, and their vascular configurations to be explored.
The development and progress of distal anastomotic intimal hyperplasia seems to be promoted by altered flow conditions and intramural stress distributions at the region of the artery graft junction of vascular bypass configurations.
The flow architectures are further illustrated with numerical examples of vascular and serpentine configuration and performance.
Multivariate analysis revealed that our clustering was a predictor of recurrence and was independent of histological grade, macroscopic configuration, vascular involvement and renal vein tumor thrombi (Table II).
First, loss of RKIP expression in the tumour centre correlates with the features of EMT and is most predictive of aggressive histopathological features including tumour budding, an infiltrative tumour border configuration, vascular invasion and distant metastasis.
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