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Vascular capacity is defined as the volume at a given pressure [19], assuming that the total intravascular volume in rabbits did not change.
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Peripheral blood flow and vascular capacity was investigated using venous occlusion plethysmography performed with an EC 6 plethysmograph (Hokanson Inc., Bellevue, USA) system.
At each measurement time point, we performed a dual energy X-ray absorptiometry (DEXA) scan to examine body composition, as well as venous occlusion plethysmography to determine the peripheral blood flow and vascular capacity.
Whilst levels of stress, and demonstrated by limited immune function and vascular capacity (e.g. peripheral blood flow), appear to be greatly reduced at the end of playing season, stress levels seem to rise again rather rapidly after training recommences, and it therefore appears that longer periods of rest may be required before full recovery is achieved.
A decrease in vascular capacity after volume reduction surgery in the presence of transiently increased cardiac output could, at least, partly explain the rises in PAP and PAOP.
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As lung volume continues to increase from FRC to total lung capacity, PVR increases and vascular capacitance decreases.
Therefore, human VPC-derived EC at the early differentiation stage might possess vascular regenerative capacity and these EC can be a valuable source for promoting vascular regeneration.
EPC number and functionality are assumed to reflect the endogenous vascular repair capacity with the EPC pool declining in higher ages and being exhausted by unfavorable life-style and risk factors.
This may translate into reduced vascular repair capacity, thereby promoting MVD in type 2 diabetes.
The pro-angiogenic and vascular repair capacity of human PACs has been consistently demonstrated in pre-clinical studies [ 23, 24].
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