Evidence Review: Three multicenter, randomized, controlled trials enrolled over 1500 adult patients with paroxysmal, unilateral paresis of cranial nerve VII and treated them with varying regimens and combinations of prednisolone, antiviral agents, and placebo, and evaluated complete recovery up to 12 months later.
Indeed, many physicians treat INH-resistant TB patients with widely varying regimens in daily clinical practice [ 20].
Recent meta-analyses have suggested a small benefit of adjuvant therapy, but the widely varying regimens and populations from the studies included in these meta-analyses have limited their impact [ 6, 7, 18, 20, 21].
Limitations include pooling data from trials conducted in distinct populations (for example, infants at high risk for asthma, or unselected populations) receiving different probiotic formulations (various organisms with a 1000 times range in daily dose) through varying regimens (prenatal or postnatal supplementation, for 1-25 months).
And while cure clearly remains the central issue, if there is a high likelihood of long-term survival and varying regimens have equal likelihood of success, it becomes imperative that long-term toxicity and effect of the treatment on QOL is also considered.
For example, in a study of factors associated with poor medication adherence in patients with COPD (n=276, average age 71 years), older patients reported that being confused about their medications or varying the regimen based on how they felt was highly correlated with poor medication adherence.
To evaluate published evidence related to bone reactions to varying loading regimens and the impact of implant design on bone tissue differentiation.
Importantly, our pharmacodynamic analysis showed that these tumor responses correlated with the degree and duration of STAT5 and Cdk1 protein loss induced by the varying dosing regimens.
The protective therapeutic potential of SAP was evaluated using varying dosing regimens.
Varying treatment regimens, unclear pathophysiology and short follow-up periods (Table 1) limit the current understanding of this association.
