Crystal structures of Mtb-AnPRT in complex with PRPP and with varying occupancies of the two metal binding sites, complemented by activity assay data, indicate that this type III PRT binds a single metal-coordinated species of PRPP, while an adjacent second metal site can be occupied due to a separate binding event.
Nickel ions in the stoichiometric or high-affinity sites (site type 0) refine to the highest occupancy of 0.94, while nickels in the potential low-affinity nickel sites have varying occupancies (45−88%) (Table 2).
The results show the essential influence of occupants on the performance, but varying the occupancy scenario does not modify the ranking between the compared alternatives.
Impedance spectroscopy (IS) measurements in the high frequency range (10 kHz–15 MHz) have been performed in samples with varying pore occupancy.
The value of n was set to 500 s. Figure 6 shows the achieved average throughput (T) in 500 s for interference with varying channel occupancy degrees and with different interference power levels.
Despite the varying ligand occupancy, all four active sites align closely.
Correspondingly, the design of DSA in distributed CWNs is crucial, yet challenging, to increasing the utilization efficiency of the wireless spectrum with dynamically-varying occupancy statuses.
These included varying the overheads, occupancy rates, and staffing costs attributed to the duration of labour care.
The Scottish Parliament will also have the power to vary the housing cost elements of UC, including varying the under-occupancy charge and local housing allowance rates, eligible rent, and deductions for non-dependents.
Starting in the early 1970s, a series of Soviet (Russian from December 1991) space stations, the U.S. Skylab station, and numerous space shuttle flights provided Earth-orbiting bases for varying periods of human occupancy and activity.
