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The complex and varying milieu of neuropathological and genetic factors underlying the development of PDD renders it difficult to provide a generalized pathophysiological mechanism across patients from this perspective to account for the common clinical picture seen.
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Wildlife live alongside humans across this array of land uses and thus, are exposed to varying chemical milieus.
RPE cells are capable of acting as efficient APCs expressing MHC class II molecules, and exposure to varying cytokine milieus may lead to RPE-mediated T cell activation or T cell regulation [31, 34].
Patch-clamp experiments show that this resistance is associated with a very small ionic current response to N-methyl-D-aspartate. Varying the ionic milieu by increasing the extracellular Ca2+ concentration, however, results in a striking increase in glutamate-induced cell death in this population.
In this context, it is important to remember that sexual hormone receptors behave as transcription factors [ 4] and that oral contraceptives (OCs) change the endogenous milieu by varying the activity of the pituitary-ovarian [ 5] and hypothalamus-pituitary-adrenal axes [ 6].
Mast cells may thus have varying effects on the inflammatory milieu in these models based on any additional environmental triggers of intestinal inflammation that may be present.
Zola examines the impact of environment by varying the social, economic, and professional milieu in which each novel takes place.
Finally, Zola examines the impact of environment by varying the social, economic, and professional milieu in which each novel takes place.
The presence of large amounts of macromolecules of varying shapes, sizes and compositions makes the intracellular milieu extremely crowded.
Likewise, our research training prompts an autonomous agentic view of students whereby we presume independent decision-making and action amidst varying contexts and environments that make up the college milieu.
Normal human breast tissue transplanted into mice may react differently to varying levels of estradiol than it does in its natural milieu in humans.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com