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Behavioral, psychodynamic, and pharmacological methods have been used with varying efficacy to treat these disorders.
Small changes in ligand structure appear to affect receptor configurations impacting co-activator binding interface and ultimately varying efficacy and potency of NR transactivation.
While past leaders have worked almost exclusively behind the scenes, with varying efficacy, that too often means that student interests are quashed.
The diet preparations available to us now are the latest in a long line of imaginative remedies of varying efficacy, but at least today's drugs benefit from a better scientific basis.
Although several therapies of varying efficacy are available, laparoscopic surgical myotomy provides the most durable long-term results with success rates between 90% and 95% for dysphagia in large studies.
Dr. Wechsler compared the varying efficacy of all prostaglandin analogues in strengthening lashes to the claims that all vitamin A analogues (retinol, retinyl palmitate and retin-A) have equal effects in improving skin conditions, which they don't, she said.
Similar(19)
Results from an mGlu5 receptor functional assay, using calcium fluorescence, revealed varying efficacies and potencies that provide evidence that subtle changes in compounds within a close structural class can have marked effects on functional activity including switches in modes of efficacy (i.e., negative to positive allosteric modulation).
Due to the varying efficacies and high costs of the new biologic agents that are currently approved for psoriasis in the United States, the precise way they fit into the range of treatments for moderate-to-severe psoriasis should be defined pending future clinical experiences.
Several inhibitors have been found to inhibit p7 channel activity with varying efficacies, including the amantadine and rimantadine (Griffin et al., 2003) that also block the influenza M2 channel (Pielak et al., 2011), hexamethylene amiloride (HMA) (Premkumar et al., 2004), and the long-alkyl-chain iminosugar derivatives (Pavlovic et al., 2005).
Part of the difference in the control of HIV replication between patients has been attributed to varying efficacies of the patient's immune responses to induce cytotoxic T lymphocyte (CTL -mediated killing of infeCTL -mediated]–[8].
Such an intervention, with varying efficacies, can be simulated through ARTIMMUS's agent‐based technology.
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