Sentence examples for vary the efficacy from inspiring English sources

Further, it is essential to elucidate the structure activity relationship (SAR) of a drug when it is conjugated with a polymer using different conjugation sites, as this can vary the efficacy and mechanism of action when compared with its free form.

19 To convert this to a proportion in the model, a Weibull distribution is fitted to the data and the proportional hazards assumption is used to vary the efficacy of the racecadotril arm with respect to the ORS arm.

First, we varied the efficacy of first-line ART when resumed after ART interruption, reflecting potential interruption-associated drug resistance.

To compensate for these limitations, we varied the efficacy parameters over their 95percentt confidence intervals simultaneously, thus testing a broad range of possibilities, and the results were comparable.

15 The efficacy of the UK comparator regimen may have been underestimated; therefore, we varied the efficacy in sensitivity analyses and found that the efficacy would have to increase by 16% for the ICER to reach £30,000/QALY.

[22], [23] Since the causes of acute diarrhea even within developing countries vary widely, the efficacy of zinc supplementation is likely to be heterogeneous.

Medical opinions vary on the efficacy of low-carb diets as well.

A sensitivity analysis varied the potential efficacy of aspirin from 30 70% with results graphed alongside the base case 50% reduction for ease of comparison.

Although the window of opportunity to initiate hypothermic treatment as well as the duration of cooling to achieve full efficacy may vary, the success or failure of therapeutic hypothermia treatment is dependent on the following four key factors [24],[15]: 1. Rate of cooling - rapid initiation of cooling immediately after injury resulted in better outcomes in animal studies.

The tools for the secondary outcomes varied among the efficacy studies as listed in Table  1.

For each vaccine and combination, for each delivery strategy, coverage level and transmission intensity, we start from a reference set of assumptions and vary one of the efficacy parameters (initial efficacy, half-life and heterogeneity parameter), at a time.