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Across all cases, overall survival and breast cancer-specific survival, unadjusted for confounders, did not vary by expression of IGF1, IGF1R, IGFBP2, or IGFBP3 (Fig. 2).
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When examined separately by individual race/ethnic groups, survival did not vary by individual protein expression for Caucasians or Japanese.
Interestingly, the occurrence of CREB and E2F1 sites varied by gene expression profile: genes that decreased in expression in co-treated cells relative to control cells contained more CREB binding sites, while positively regulated genes contained more E2F1 binding sites.
However, statistical evidence of an interaction was observed between tumour expression of BRCA1 and route of administration for OS (P=0.014), suggesting that treatment efficacy for IP vs IV was modified by expression level of BRCA1. Figure 2 illustrates the extent to which the OS and PFS varied by tumour expression of BRCA1 and route of administration of therapy.
Vertebrates express four distinct CK isozymes, and patterns of expression vary by tissue and by developmental stage.
The plastic surgery dataset [2] contains frontal face images of plastic surgery-altered faces, which vary by scale and small expression, small pose, and majorly by plastic surgery procedures.
We observed minimal difference between groups suggesting that changes in T-cell response to IL-7 are unlikely to be due to difference in levels of receptor expression although expression does vary (by a factor of approximately 2) at the protein level within each clinical group.
Our results indicate that the immunological effects observed in the lab are largely generalizable to the natural environment, but that effect size and/or absolute levels of cytokine expression vary by location.
Here we examine whether the benefits of physical activity vary by the tumor protein expression status of ER, PR, HER2, and p53 in order to provide greater insight into biological mechanisms underlying the association between physical activity and risk of breast cancer.
We had CD4+ lymphocytes from European-American CAMP subjects only, and it is possible that coexpression results would have differed had we additionally had expression profiles from subjects of other ethnic backgrounds, as gene expression can vary by ethnicity.
Moreover, SSR expression can vary by tumour cell type and over the time course of disease.
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