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Climatic conditions such as elevated temperature, rainfall and air humidity, as well as urban structures without adequate sanitation, are factors that contribute to the active dispersion of the mosquito and the dissemination of the various virus serotypes [ 12].
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Analyses of dengue virus serotypes showed that various serotypes were circulating in each of these countries during this period.
Dengue is endemic in tropical countries worldwide and the four dengue virus serotypes often co-circulate.
This chimeric antigen incorporates the envelope domain III (EDIII) of the four dengue virus serotypes.
But it had limited efficacy against dengue 2, one of four dengue virus serotypes in circulation.
An initial infection with one of the four distinct dengue virus serotypes is typically mild.
The four dengue virus serotypes (DENV1-4) aresponsibleble for the most prevalent mosquito-borne viral illness in humans.
Serotype identification confirmed 170 DENV-1 infections, 73 DENV-3 infections, and 1 co-infection with both virus serotypes.
Subsequent immunofluorescence assay analyses using monoclonal antibodies against yellow fever virus and all 4 dengue virus serotypes were negative.
The surveillance of active dengue virus activity during inter-epidemic periods provides information on prevalent virus serotypes in the area.
The vaccine was safe and generated antibody response for all four dengue virus serotypes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com