Longitudinal studies with repeat neuropsychological testing support multivariate approaches to model the effects of various types of pathology on dementia risk and cognitive decline.
The Helicobacter pylori bacterium is characterized as the causative agent of various types of gastric pathologies.
Ultimately, IHC for alpha-synuclein (αS), which is its major molecular component [ 168], is the most sensitive and specific gold standard to detect various types of Lewy pathologies.
This task has the added bonus of allowing us to measure interval-timing performance, which is a good indicator of various types of neuropathology, including pathologies of the basal ganglia circuits (Paule et al. 1999; Matell & Meck 2004).
However, when these transgenic/knockout mice are tested using models that develop various types of age-related pathology, they show alterations in progression and/or severity of pathology as predicted by the oxidative stress theory: increased oxidative stress accelerates pathology and reduced oxidative stress retards pathology.
As part of the SPIN project, we defined an XML schema (available at the SPIN website), which can accommodate the various types of information contained within a pathology report.
Among the subjects enrolled, 23 had no known ocular pathology (39 eyes), 7 were highly myopic without any other retinal pathology (14 eyes), and 19 were patients with various types of NIU (23 eyes).
Exposure to various types of asbestos can lead to fibrotic lung disease (asbestosis); a range of non-neoplastic pleural pathologies including pleural plaques, diffuse pleural thickening, pleural effusions, and rounded atelectasis; and cancer.
Given the differing etiology, pathology, signs and symptoms, and progression of disease between the various types of dementia, 56 and also the differing rates of falls, 5 there is value in future studies focusing on a specific diagnosis.
Inconsistencies between different studies might be attributable to the heterogeneity of underlying vascular pathology in AD as cerebrovascular changes can occur concomitantly with AD pathology, and also because CAA may contribute to the development of various types of cerebrovascular diseases such as lobar hemorrhage, microbleeds, and white matter lesions [ 39].
