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In this first issue of Intensive Care Medicine Experimental, two related studies describe the effects of antibodies directed against adrenomedullin (ADM), a vasoactive peptide that is released from various tissues during systemic inflammation, in murine sepsis.
We found that AtPV42a and AtPV42b were expressed in various tissues during different developmental stages.
H19 and IGF2 are expressed in various tissues during development and down-regulated in most mature tissues [35].
This low efficacy may have been caused by unexpected transgene expression in various tissues during the embryonic stage, because the activin signal is important for normal development.
In addition to being an early step in tumor metastasis, EMT is known to be associated with many pathophysiological situations, such as formation of various tissues during embryonic development [5], and of keratinocytes during wound healing [6].
The allele used in this study, in its first stage before combination with a FLP recombinase, could also be exploited to detect the activity of the PTBP1 locus in various tissues during ontogeny as exemplified by our data for embryonic developmental stage E12.5 and E16.5.
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Quantitative real-time PCR analysis showed that ChAkt1 mRNA is broadly expressed in various tissues and during different stages of the oyster's embryonic and larval development.
In studies of the expression of large miRNA sets, enrichment or depletion of miRNA binding sites and 3' UTR length have been evaluated with respect to gene expression in various tissues and during development.
Although some OBPs appear to be exclusively involved in odor detection, others are expressed in various tissues and during different life stages (see [2] for a review), which suggests that the protein family can serve multiple functions.
The function of these transcripts, in various tissues and during early development, remains to be determined.
In this study, we examined the expression pattern of FoxO6 in various tissues and during myogenic differentiation at both mRNA and protein levels.
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