Sentence examples for various tissue compartments from inspiring English sources

Therefore, the efficacy of therapy and the selection of resistances could be related to intracellular concentration of the drugs and to their ability to cross biological membranes and penetrate into various tissue compartments.

In this context, T cell mediated immune responses were assessed by ELISPOT from various tissue compartments specific to the route of immunization 45 days after vaccination.

DC interact with pathogen infected/exposed cells in various tissue compartments as part of the immune surveillance function in vivo [16], [17].

This being more consistent with some reports describing a preferential role for CD86 in regulating IL-10 production and is consistent with our previous description of differential CD86 expression in various tissue compartments in CLP, with increased levels of CD86 found in PL compared to blood [22].

Finally, a decrease in peripheral blood pDCs has been shown to be associated with HIV infection, and previous studies have indicated that HIV-mediated pDC activation leads to the upregulation of CCR7 and the production of CCL2, CCL3, and CCL4 [24], [26], [26], which may lead to migration of pDCs to various tissue compartments.

The use of SQUID will enable a quantitative determination of the distribution of VSOP to various tissue compartments, which can be compared between healthy controls and EAE mice at different time points during disease.

Further studies are needed to elucidate a possible relationship between insulin sensitivity, various adipose tissue compartments and adipokines and related molecules in various ethnic groups.

Information on the levels of angiotensin II (Ang II) and its receptors in the various renal tissue compartments is still incomplete.

Further studies are required to determine the temporal dynamics of the engrafted T-cell repertoire in various murine tissue compartments and identify when it most closely resembles that of patients' lymph nodes.

Here, we review recent advances in the design and synthesis of nanostructured mesoporous materials, focusing on SBA-15, and highlight opportunities for the delivery of biological agents to various organ and tissue compartments.

Cytochrome P450 monooxygenases (CYP) play an important role in the defense against inhaled toxicants, and expression of CYP enzymes may differ among various lung cells and tissue compartments.