In view of this approach, various target-specific NIR conjugates have been reported for targeting tumor imaging, e.g., tumor integrin, αvβ3 [4], tumor growth factors or their receptors [18], [26] [30], glycoprotein [31], or tumor specific protease [21].
But several target specific groups.
There is currently no cure or approved medication for FXS although various drugs target specific disease symptoms and a large number of therapeutics are in various stages of clinical development.
There is currently no cure or approved medication for fragile X although various drugs target specific disease symptoms and a large number of therapeutics are in various stages of clinical development.
Our results buttress the idea that, in the developing brain, the various organophosphates target specific neurotransmitter systems differently from each other and without the requirement for cholinesterase inhibition, their supposed common mechanism of action.
Our results bolster the idea that, in the developing brain, the various organophosphates target specific neurotransmitter systems differently and without the requirement for cholinesterase inhibition, their supposed common mechanism of action (Mileson et al. 1998).
NK cells are one component of the innate immune system, able to recognise various targets without specific sensitisation.
The results of those pharmacological studies listed in Additional file 4: Table S2 suggest that AKI in principle can be prevented or its effect diminished, and a combination of various drugs, targeting specific AKI-induced pathways and molecules, could be a way forward in disease prevention or therapeutic intervention.
In the present study, the interplay between membrane targeting and phosphorylation of eNOS was investigated by using various mutants designed to target specific subcellular locations or to mimic different phospho states.
In addition, using chemical inhibitors for various signaling pathways and target specific siRNAs, we dissected the role of EGFR-MEK1/2 pathway in regulating CIP2A expression.
Cancer research has become increasingly focused on the potential of various small molecule inhibitors to target specific proteins in signaling pathways that are commonly overexpressed in cancer.
