But for all the weightiness of the enterprise, the atmosphere is that of a country festival, where various subpopulations share a common interest while pursuing it in very different ways.
Recent progress has allowed the identification, analysis, and experimental manipulation of various subpopulations of Tregs.
Various subpopulations, such as overweight and obese individuals and aging adults, exhibit greater sensitivity to the effects of reduced salt intake and may gain the most benefits.
Furthermore, the broad time resolution (picoseconds to hours) of MFD allows for kinetic studies that resolve interconversion events between various subpopulations as a biomolecule of interest explores its structural energy landscape.
These various subpopulations may include cancer stem cells, mutated clonal variants, and tumor-associated stromal cells, as well as cells experiencing a spatially different condition such as hypoxia within a diffusion-limited tumor region.
Attention must also be given to differential effectiveness of similar interventions among various subpopulations.
The same work also demonstrates regeneration of whole populations from various subpopulations in hematopoietic systems.
All these cells have large dendrites by which they spatially integrate over various subpopulations of local motion detectors.
Figure S1 shows QRT-PCR data for expression of the TGF-beta superfamily member GDF3, a gene which is strongly downregulated across the various subpopulations, for four ES cell lines subjected to separation by flow cytometry.
In subsequent experiments, we quantified γH2AX-foci at 8 h and 24 h after irradiation with 2 Gy, to find out whether genotoxic insults such as ionizing radiation differently affect these various subpopulations.
Specific demographics of the various subpopulations of the safety population are listed in Table 2.
