Thus, to what extent TSAd functions as a general adapter protein in regulating cellular migration through various signalling pathways remains to be established.
The involvement of HPK1 in various signalling pathways implies a complex pattern of regulation which might partially account for the controversial results gained from T-cell studies on HPK1-mediated regulation of AP-1 activity and IL-2 transcription [23], [38] [41].
FHL2 plays an important role as molecular transmitter linking various signalling pathways to transcriptional regulation.
As a consequence, Bcr-Abl organises a multimeric protein complex and activates various signalling pathways [ 11, 12].
In addition, anthracyclines have been shown to modulate various signalling pathways including those involved with apoptosis [ 5, 6].
The latter domain of CD44 recruits regulatory proteins to the cell membrane activating various signalling pathways [ 35, 36].
Cisplatin activates various signalling pathways that include the DNA damage response (DDR) and the PI3K-Akt pathways [ 1].
The manuscript provide a brief survey of the recent findings and discuss about various signalling pathways operating in germline stem cell niche.
25 VEGF activates various signalling pathways such as phosphatidylinositol 3-kinase (PI3K /Akt, protein kinase C (PKC) and mitogen-activated protein kinase (MAPK) cascades.
Salicylic acid (SA), jasmonate (JA), and ethylene (ET) contribute to responses to biotic stresses by influencing various signalling pathways with complex networks of synergistic and antagonistic interactions [ 2].
These findings indicated that NRDc regulates various signalling pathways by promoting ectodomain shedding, but its role in cancer biology is unknown.
