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The relationship of selected answers was compared among various responder groups by using three-dimensional contingency tables.
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Using one-way ANOVA, we analyzed whether changes in the various continuous scores were greater in higher ACR responder groups, and whether these differences were statistically significant at the group level.
The patients were further classified into responder and non responder groups based on 50% improvement criteria.
Even the severity scores of various symptoms in the responder group were observed to decrease drastically when compared to their non-responder group patients.
In therapeutic response, however, patients with the Met/Met genotype were significantly more frequent in the non-responder than in the responder group.
At baseline, the mean LDQ total score was slightly higher in the Non-Responder group than in the Responder group (12.08 ± 2.14 vs. 11.94 ± 1.98).
The fact that the non-responder group had a lower AUC-CSH therefore shows that it has a more heterogeneous distribution of 111In-ibritumomab thanethe than the responder group.
In SPECT/CT voxel-based histogram analyses of 111In-ibritumomab tiuxetan uptake, the non-responder group showed a more heterogeneous distribution than the responder group.
Mean duration for improvement among the responder group was 3.2 ± 1.9 days.
All the partial responders were included in the responder group.
In the responder group, the mean (s.d).
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