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These lipid mediators exert their autocrine and/or paracrine functions through various receptor types with different location and signaling pathways [ 45].
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To define the EP receptor(s) involved in PGE2 signalling in this experimental setting, we used agonists for the various EP receptor types.
Ultimately, the type and magnitude of both direct and indirect effects on various receptors and other types of impacts are evaluated in relation to exposure-dose potential by all relevant pathways.
It is believed that these receptor types all differ in their relative sensitivity to various odorants.
For example, some single 10-RANCs might have inputs from receptor types labeled 1 10 for odors whose discrimination depends on various combinations of those receptor responses, and some single 14-RANCs could have inputs from receptor types 6 19.
Probably the long term incubation leads to higher likelihood of IFN-γ production since the protein processing may be performed by a higher number of T cell populations with various T-cell receptors types with consequently a better antigen presentation than in short term culture (1-day).
Comparing the time courses of bound receptors of various types with receptor trafficking with the case where there is no trafficking, it was found in [3] that trafficking apparently facilitates receptor binding.
activin receptor type IIB.
ADCYAP receptor type I gene.
TGF-β receptor type III.
Moreover, curcumin has the ability to inhibit both VEGF and its receptor in various cancer types; it might be useful as an antiangiogenic agent [ 64, 65].
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