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Sirtuins act on various proteins, including histones, which are important for organizing the DNA in cells.
Caldicellulosiruptor bescii is a cellulolytic/hemicellulolytic anaerobe, which extracellularly secretes various proteins, including multidomain cellulases with two-catalytic domains, for plant biomass degradation.
NAD+ is utilized by various proteins including sirtuins, poly ADP-ribose polymerases (PARPs) and cyclic ADP-ribose synthases.
As expected, the ~47-kDa fragment of truncated calcineurin showed high phosphatase activity independent of Ca2+/CaM and was thus capable of catalyzing the dephosphorylation of various proteins, including Drp1.
Gao's team used a form of polymerase chain reaction analysis to scan the cells for signs of various proteins, including some previously found in stem cells and some known to play a role in prostate development.
Small amide derivatives have been shown to affect a wide range of molecular pathways through allosteric regulation of various proteins including proteases [39], [40], the cannabinoid receptor 1 (CB1) [41], the α7 nicotinic acetylcholine [42] and GABAA receptors [43].
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Applying a cutoff of ≥2-fold enrichment for Ku-specific binding, we identified several known Ku interactors as well as various other proteins, including CUL4A.
alpha-crystallin (alphaA and alphaB) is a major lens protein, which belongs to the small heat-shock family of proteins and binds to various cytoskeletal proteins including actin, vimentin and desmin.
Hsp90 is a molecular chaperone that drives folding and stabilization of various cellular proteins, including BRAF.
The basal lamina is made up of various ECM proteins, including fibronectin, collagens and laminins.
These MHC class II proteins interact with various pathogen proteins including pathogen membrane proteins and yet uncharacterized proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com