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Various preclinical studies have demonstrated that nanoformulation within ferritin nanocages significantly improved targeted therapy and accurate imaging of cancer cells.
γ-Oryzanol (OZ) is reported for anti-oxidative, anti-inflammatory, anticancer, anti-hyperlipidemic, and anti-diabetic effects in various preclinical studies.
Various preclinical studies and clinical trials using these advances have shown that tissue-engineered materials are a viable option for surgical repair, but require refinement if they are going to reach their clinical potential.
This review gives an insight on the various preclinical studies performed in the area of tissue engineered vascular grafts highlighting the different strategies used with respect to cells and scaffolds, typical animal models used and the major in vivo evaluation studies that have been carried out.
Antibacterial coatings may prevent bacterial adhesion and biofilm formation, according to various preclinical studies.
28 The pharmacology of degarelix was initially assessed in various preclinical studies.
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Several preclinical studies in various animal models report the effectiveness of both ACP [9, 10, 11, 12, 13, 14, 15, 16] and HA CMC gels [8, 17] or HA-CMC membranes [18, 19] for preventing postsurgical adhesions.
Several preclinical studies have evaluated the effects of various strains of LAB probiotics on symptoms and clinical markers of arthritis.
In recent months, there have been several preclinical studies evaluating the efficacy of RG7388 in various cancers.
Because of the relative radiosensitivity of colorectal carcinoma and the availability of mAbs against CRC-associated antigens, the efficacy of RIT using radiolabeled mAbs against CRC has been investigated in various preclinical clinical studies.
The only consistent observation among the various IA preclinical studies was the sporadic formation of small foci (generally no larger than 1-5 mm in diameter) of bone along the needle track between the skin and the outside of the joint capsule.
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