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This feature has been reported consistently in various population studies [23, 24].
Based on various population studies, the incidence of LSS is in the range 5 50 per 10,000 individuals [2, 3].
Our results are consistent with previous reports from various population studies and also findings on the evolutionary dynamics of each subtype.
While the risk of familial recurrence has been evaluated in various population studies, little is known about the genetic pathogenesis of CHD.
The present paper was planned to understand the genetic susceptibility to lead toxicity in the various population studies conducted worldwide and also to correlate it with the current scenario in Saudi Arabia.
These findings are in keeping with recent studies that have shown that in various population studies not particularly targeting patients with diabetes that visit-to-visit variability in SBP is a powerful predictor of stroke and coronary events, independent of mean SBP (9, 10).
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Owing to the different allele and genotype frequencies in various populations, studies on FPR1 haplotypes in different racial groups were also carried out.
Because of difference in endothelial parameters among various populations, study of normative data of each population is important.
Because endothelial parameters differ between various populations, study of normal data from each population is essential [ 30].
This approach was used, also in the Icelandic population, to identify a missense substitution (R47H) in the TREM2 gene, with an allele frequency of 0.12 0.63 % in the various populations studied, that confers a threefold increased risk of Alzheimer's disease (Jonsson et al. 2012).
The inconsistent finding of RA association with the +49G allele at the cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) gene [25], along with the finding of only nominal association at this locus in the WTCCC study, is probably influenced by differences in the demographics of the various populations studied.
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