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Simultaneous exposure to various POPs in the general population may contribute to development of obesity, dyslipidemia, and insulin resistance, common precursors of type 2 diabetes and cardiovascular diseases.
Rather, they could be surrogates of exposure to a mixture of POPs in the general population because there are high correlations among serum concentrations of various POPs in the human body.
The TEQ values can be calculated using toxic equivalency factors (TEFs) that express the toxicity of various POPs in relation to the most toxic dioxin, 2,3,7,8-tetrachlorodibenzo- p-dioxin (TEF = 1) (Van den Berg et al. 2006).
Although the proposed PBPK model framework for POP lifetime exposure assessment in women is constructed on validated descriptions of absorption, distribution, metabolism, and excretion of various POPs in rodents or humans, further studies are needed to validate the model.
Surprisingly, we observed a positive association between concentrations of various POPs in adipose tissue and in blood and the improvement of HOMA-S (indicator of insulin sensitivity) and HOMA-B (indicator of pancreatic insulin secretion) after surgery even after adjustment for body fat mass variations.
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Council Speaker Christine Quinn gave opening remarks -- the standard variety -- various Representatives popped in, waved, exited swiftly.
It seems likely that differing sex-hormone mimicking effectsex-hormone mimicking, as shown in vitro (Boneffectsofgensen ethel. 2001), might contribute to the divarious effects regarding the levels of rePOPsuctive hormones.
The NHANES data provided a unique chance to investigate the possible associations between serum concentrations of various POPs and CVD in a random sample of the general population, despite the recognition that self-reported CVD as the dependent variable is less accurate than physician-diagnosed CVD.
Various POPs, which mainly accumulate in adipose tissue, may play a critical role in the current epidemic of type 2 diabetes.
Mr. Wildhorn's absence from Broadway since his 2004 adaptation of "Dracula" has not exactly occasioned widespread hand-wringing, and his competent rendering of various pop styles in "Wonderland" probably won't win him a host of converts.
Pearson correlation coefficients of various POPs with Alu and LINE-1 assays are displayed in Table 4.
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