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Until we discover the cause, most likely we will end up using cocktails of drugs targeting various pathways with small incremental benefits, much like we do for cancer.
The recovered proteins were unevenly distributed between various pathways, with a large proportion of components of the chromatin assembly pathway being present in both PfCK2β1 and PfCK2β2 precipitates, implicating PfCK2 in chromatin dynamics.
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The model effectively incorporates the various pathways patients with moderate COPD could undergo.
In each cell type we also observed a repeated enrichment of modulated genes involved in various pathways associated with oncogenesis.
GSOA prioritized pathways known to be dysregulated in either USC or UEC, as well as various pathways associated with cancer development in general.
Various pathways associated with the cytoskeleton are also enriched, suggestive of a change in cellular growth in an effort to overcome toxic effects and to regenerate damaged tissues.
Combined with the existing tools for biochip analysis, K.-F. Lee et al. identified the various pathways associated with the exposure to differing doses of radiation and the potential gene-microRNA interactions that regulate these pathway changes.
To better understand the various pathways associated with taxane resistance, our laboratory selected MCF-7 breast tumor cells for survival in increasing concentrations (doses) of paclitaxel (MCF-7TAX-1 cells) [ 24] or docetaxel (MCF-7TXT cells) [ 23].
Central to the improvement in understanding of hydrothermal processes is the need for fundamental information on the kinetics of the various pathways associated with the deconstruction of lignocellulosic biomass.
These differences suggest that various pathways are associated with the anti-inflammatory effects of lactobacilli.
Also the interhemispheric propagation didn't show any barrier at the midline, and the propagation of SSOs to contralateral sites is consistent with various pathways.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com