Sentence examples for various pathway databases from inspiring English sources
The C2Cards will increase the awareness of the differences that exist between the various pathway databases.
The various pathway databases available differ in a number of ways and all have their own strengths and weaknesses.
The existing constraint-based approaches for metabolic engineering have proven useful, but are limited only to reactions catalogued in various pathway databases.
However, they are focused on the union of various (pathway) databases instead of explicitly pointing out the differences between pathway databases.
Combining all the knowledge on the metabolic network contained in the various pathway databases and identifying conflicting information is, however, far from trivial.
The final step included a manual verification and curation of the reference network to prune and refine it using literature reviews and various pathway databases (e.g. Biocarta, KEGG).
The identification and prioritization of latent nodes and edges (connectivity between stimuli, latent nodes and measured nodes) were conducted using various biological pathway databases (e.g. KEGG, Biocarta) and the ensemble network published by Kirouac et al. (2012), embodying the union of several online pathway databases.
For GSEA analysis (http://www.broad.mit.edu/gsea/index.jsp), we used the molecular signature database C2, which contains 1892 curated gene sets that are collected from various sources including online pathway databases and knowledge of domain experts.
The Molecular Signatures Database (MSigDB) [ 13] is a database that collects gene sets from various sources, including online pathway databases, publications in PubMed, and the knowledge of domain experts.
Hence, it is very much important to involve various pathway curator communities in the database development, such that continuous flow of new information can flourish the database.
> Besides these pathway drawing and pathway editing tools, a huge effort is also observed to develop various pathway analysis tools by different database developers.
