Sentence examples for various pathogenic pathways from inspiring English sources

Modeling CP as a complex syndrome resulting from various pathogenic pathways with or without recurrent trypsinogen activation allows for the direct assessment of the effect of SPINK1 polymorphisms in the development of CP.

In consideration of the frequently reported, only partial efficacy of the blockade of a single cytokine, the next research challenge might be represented by the opportunity of exploring, in carefully selected asthmatic subjects, the effects of different cocktails of biologics targeting the key pathogenic pathways underlying the various phenotypic subgroups of asthma.

Finally, these data should still be cautiously interpreted because the suggested mediators may simply be statistical intermediates and/or markers of various pathogenic processes not essentially on the causal pathway to HCC.

We have found that a multi-modality therapeutic approach to prevent various pathogenic cascades – such as antibody-driven complement activation, other immune pathway activation, thrombosis, and tissue ischemia-reperfusion injury – has met with progressively greater success to protect the xeno lung from injury.

It was shown that mutations in ERG6, an important gene in the ergosterol biosynthesis pathway, can lead to AmB resistance in various pathogenic species of yeast [48], [49].

First, ARDS is a heterogeneous syndrome including various pathogenic mechanisms that may or may not be related to the endocan pathway.

The phenomenon is attracting attention not only from an evolutionary perspective, but also because of its confounding implications for accurate genome annotation and metabolic pathway reconstruction, and for its potential in highlighting drug targeting opportunities against various pathogenic organisms [1], [3], [4], [64], [65], [66], [67].

General information on various pathogenic apicomplexans is available through MicroWeb.

From this joint effort, major pathogenic pathways emerged.

SL1067 is a potent tool for studying various processes in which IL-1α is engaged but the specifics remain undefined, e.g., Caspase-1 dependent IL-1α secrethen59, the potential for IL-1α/IL-1RI complex to function as an autocrine growth factor38, and the regulation of functional IL-1α activation by IL-1RII in necrosis17, as well as its role in numerous pathogenic pathways.

It is bactericidal against various pathogenic gram-positive bacteria, but not against commensal bacterial flora55.