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It is believed that prolonged, uncontrolled hypertension leads to cardiovascular diseases and various organ damage cases.
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First, it is well established that glucose overload imposes oxidative stress to cells and that chronic hyperglycemia leads to various organ damages.
Further, because chronic HIV infection results in various forms of organ damage, and because PLHIV are as vulnerable to unconnected illnesses as other people, it is also essential to ensure their access to general health facilities.
Deterioration stage – Various organs are damaged due to long-term drinking.
Multiple myeloma is a hematological malignancy characterized by abnormal proliferation of monoclonal plasma cells in bone marrow leading to various end-organ damage including anemia, hypercalcemia, renal insufficiency and osteolytic bone disease [ 1].
In MCL, MC are particularly immature and show rapid proliferation in various organs with consecutive organ damage (1).
Amyloidosis is a rare disorder characterized by abnormal, misfolded proteins that accumulate in various organs, causing progressive organ damage [ 1, 2].
Autoantibodies are detectable before the clinical onset of SLE and with the development of organ damage various specific autoantibodies appear in the circulation.
IL-6 is also associated with organ damage in various hemorrhage models (Fig. 3) [ 23, 42].
Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease characterized by various systemic symptoms and multiple organ damage.
Given their unique abilities of site, specific migration, plasticity and potential for tissue repair or regeneration, stem cells and their relationship to repair injury or damage in various organ systems have recent interest.
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