Sentence examples for various mutations in from inspiring English sources

Cancer is caused by various mutations in hundreds of genes including both proto-oncogenes and tumor suppressor genes.

Driven by various mutations in the β-globin gene cluster, the disease is characterized by a reduction or absence of β-globin gene expression.

Various mutations in PARK2 gene, which encodes the protein parkin, are significantly associated with the onset of autosomal recessive juvenile Parkinson (ARJP) in neuronal cells.

When Gollob and his colleagues examined the tissue samples, they found that four of the 15 patients had various mutations in GJA5.

Using a combination of laboratory assays and computer algorithms, the team tested various mutations in HB36.5, looking for single amino acid changes that would increase how tightly the protein bound to a diverse group of hemagglutinins.

We explored the possibility of employing more than one PCR fragment to introduce various mutations in a single step, and found that when up to five PCR fragments were co-transformed into yeast, the recombination frequency was maintained as the number of fragments was increased.

Various mutations in the MID1 proteins have been identified in OS patients [1], [3], [10], [12] [17].

We first detected how the various mutations observed in Actinopterygian ARs are located in function of the complex evolutionary history described above.

Structure-function studies of TPPI are necessary to identify the molecular mechanisms associated with various mutations occurring in LINCL to develop proper strategies for rational therapeutic intervention.

Standard PCR-directed mutagenesis approaches were used to generate the various mutations used in the study and all mutations were verified by automated dideoxy sequencing.

There were various mutations identified in the SULT enzyme family and they were reported to exhibit different catalytic specificity and capacity in each polymorph form [ 15].