The researchers who study these various mouse models acknowledge that they differ from humans in many critical ways.
Since none of the currently available animal models of IBD reflects all aspects of IBD in humans, we used various mouse models of chronic colitis.
Physiological and pathological changes were examined using islets from various mouse models such as non-obese diabetic (NOD), ob/ob, db/db mice and during pregnancy.
This nanoprobe enables in vivo precise quantification and tracking of the number and dynamics of neutrophils in both superficial and deep tissues in various mouse models of inflammatory diseases, including peritonitis, paw edema, colitis, and acute lung injury.
The application of this protocol permits the design of experimental studies with direct evaluation of SR Ca2+ in real time in various mouse models of cardiac disease, including transgenic animals harboring mutants of RyRs or other Ca2+ signaling proteins.
Since then one of the most important advances in HD research has been the generation of various mouse models that enable the exploration of early pathological, molecular and cellular abnormalities produced by the mutation.
These cellular studies were generally completed by preclinical studies showing a reliable antitumoral effect in various mouse models.
Here, we developed a methodology to investigate production and fate of both Hep-1 and -2 peptides in various mouse models for iron metabolism disorders.
Numerous studies using various mouse models have demonstrated that phenotypic noise can suppress or worsen lethal phenotypes among various genetic backgrounds.
Neutralizing antibodies induced upon immunization were specific to C5a and they did not alter C5/C5b activity significantly but led to attenuation of arthritis in various mouse models.
Consistent with this, adenosine levels are elevated in various mouse models exhibiting features of chronic lung disease [23], [24], [25], [26].
