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Chimpanzees across Africa had various malaria parasites; bonobos, their closest relatives, did not.
Using a cross-sectional approach, this study investigated various malaria risk factors among residents of Mgedula Village, a malaria-endemic community located in Jozini Local Municipality, UMkhanyakude District, South Africa from May to August 2014.
There is need to understand how various malaria risk factors interact at the individual, household and community levels, as well as wider contexts, in order to guide the design and implementation of effective and more comprehensive control strategies.
This can be attributed to the various malaria prevention strategies which have been put in place such as: Education campaigns.
Further field studies in different endemic countries will help to optimize its use for various malaria control applications and as a point-of-care tool.
These results will provide highly valuable information in the context of integrated studies combining linkage and high density association studies for various malaria traits and conditions.
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To further explore Pfserca sequence diversity and to look for possible causes and geographical structuring, we sequenced a large panel of field isolates from various malaria-endemic geographic areas before widespread deployment of ACT.
In order to develop an efficient test for diagnosis of malaria, a profound understanding on various malaria-related biomarkers is prerequisite.
Moreover, additional studies are needed in various malaria-endemic areas to determine if the findings here can be replicated, since the association we observed between microbiota composition and P. falciparum infection risk may have occurred by chance or may be confounded by other factors not measured in this study.
There are several malaria vaccine candidates at various stages of development.
Immune response against circumsporozoite protein (CSP) of Plasmodium berghei, a major surface protein on the sporozoite, confers protection in various murine malaria models.
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