Sentence examples for various loci using from inspiring English sources

We show that this approach can be applied at various loci using multiple engineered nuclease platforms, including transcription-activator-like effector nucleases (TALENs), RNA-guided endonucleases (CRISPR/Cas9), and zinc finger nucleases (ZFNs), and in different cell lines to identify conditions and strategies in which the desired engineering outcome has occurred.

We did not see significant changes of chromatin accessibility at various MHC II loci using FAIRE, which does not exclude the possibility that other genomic loci in this area might show differences in chromatin organization.

Genotyping is not possible as the mutated loci are as yet uncloned, but we refer to the various combinations of loci using the hypothesis that plants bearing silent transgenes are heterozygous for the recessive mutant or homozygous wild-type, while plants with active transgenes are homozygous for the mutation.

These short sequence reads (tags) are then aligned to a reference genome and binding sites are identified on the basis of their significant accumulation at particular genomic loci using various peak detection algorithms [ 4].

To elaborate our hypothesis and to gain supporting theoretical evidence, we undertook a bioinformatic analysis of the SLC6A3 locus using various genomic databases and computational analytical tools available via public domains (Table 1).

However, by virtue of mendalian inheritance, each locus is independent from every other locus; the high number of loci used in DNA fingerprinting obviates the same issue.

Slide preparations were hybridized with the various locus-specific probes using codenaturation and overnight hybridization.

This chapter presents step-by-step methods of constructing of various loci, which are widely used in various engineering applications.

The various loci were amplified by PCR using the primers described in Supplementary Table 5. Assays were performed with the Surveyor mutation detection kit (Transgenomics) as described41.

The guide sequences in the sgRNAs used for targeting the various loci are shown in Supplementary file 1D.

Alignment was performed on individual genes with sequences from other copepods using Probalign to estimate sequence divergence of various loci.