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That is, stress itself is not necessary; activation of the RpoS response in unstressed cells that have an I- SceI-produced DSB was sufficient to cause mutations during repair of the DSB 11, 12. RpoS appears to allow the use of four lower-fidelity DNA polymerases in DSE/DSB repair, creating various kinds of mutations.
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In these early mutageneses, several kinds of mutation were detected.
These mutations undergo various kinds of selection, including the shaping of the signal sequences on the chromosomes [ 14] (see above).
This method has been shown to detect EGFR mutations in various kinds of clinical samples including pleural fluid and surgically resected tissues from patients with NSCLC [ 30– 30].
Even though PIK3CA amplification and somatic mutation have been reported previously in various kinds of human cancers, the genetic change in PIK3CA in human breast cancer has not been clearly identified.
Buffering mechanisms that protect against those various kinds of perturbations have the consequence of reducing the sensitivity of the organism to an inherited mutation, even if the original buffering mechanism arose to protect against environmental or developmental perturbations.
The issue begins at the whiteboard fastidiously counting bits, gradually moves into the more abstract world of inferring various kinds of gene networks and ends near the clinic reviewing methods to detect diabetes biomarkers and cancer driver mutations.
Overexpression or mutation of the ErbB receptor is closely correlated with the incidence of various kinds of human cancer [1], [2].
Writer lists the various kinds of pasta.
There are various kinds of grammatical conditioning.
Describes the various kinds of machines operating.
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