Sentence examples for various isoforms the from inspiring English sources

c-FLIP exists in various isoforms, the best-characterised are c-FLIP long (c-FLIPL) and c-FLIP short (c-FLIPS).

However, because CD44 is ubiquitously expressed in various isoforms, the value of CD44 as a CSC marker is controversially discussed [ 23].

With the discovery of the various isoforms of the PRLR, a more detailed analysis of the cellular localization of the receptor as well as possible differences between subtypes of breast cancer was warranted.

We show here for the first time that the p110β among the various isoforms of the PI3K p110 catalytic subunit is commonly overexpressed in a subset of ovarian serous carcinoma compared to the benign serous tumor, and that β-isoform overexpression is associated with PTX resistance in ovarian cancer cell lines.

One caveat is that cytoplasmic WT1 protein could be of one specific isoform, as antibody staining cannot distinguish amongst the various isoforms of the WT1 protein.

The role that ApoE isoforms play in disease development seems to be closely associated with different affinities of the various isoforms for the low density lipoprotein-receptor and lipids themselves.

Cyclic AMP is formed from adenosine triphosphate by the action of various isoforms of the enzyme adenylyl cyclase (AC), each of which is specifically regulated by G proteins, calcium, and other modulators (1).

9, 18 The overexpression of genes encoding various isoforms of the cytokinin pathway rate-limiting enzyme IPT can enhance the levels of plant cytokinins.

In other words, more than one isoforms of these genes displayed differential expression between non-oncogenic and cancer samples, but the gene-level expression differences were cancelled out by the combined effect of various isoforms of the same gene.

Our combined results demonstrate that the EZH2 locus gives rise to various isoforms, confirms the existence of two major isoforms (EZH2α and EZH2β) at both the mRNA and protein levels, and shows their localization in tissue by immunohistochemistry.

These included induction of many probe sets that detected various isoforms of the killer cell immunoglobulin-like receptor that inhibits the activity of the MHC class I receptor.