A systems biology approach to infectious disease research, which models various interacting component networks, will permit greater understanding of the molecular mechanism and the interplay between the host and pathogen.
The mathematical model depicts interacting components but not processes or mechanisms by which they interact.
We apply this technique to various interacting particle systems.
Interactions: green connections show activation of downstream interacting component; red connections show inhibition of downstream interacting component; and black connections show physical binding between components.
The aim of the present study is to pursue intuitive representation of various, possibly interacting, types of biological systems described as interconnected physical components, such as mass and energy storage elements, active and passive transport or biochemical transformations.
Each membrane component interacted with various components in the blood in a desired sequence.
While the homogeneity condition does not lead to loss of accuracy while simulating various continua, it fails to offer detailed solutions when applied to systems with dynamically interacting heterogeneous components.
Previous studies shed light on various aspects of the RHIS but fail to provide a comprehensive picture of the RHIS, how it is organized and how various RHIS components interact with each other to influence RHIS performance.
As some IAPs regulate apoptosis by interacting with various components of the MAPK family (Zhang et al, 2003; You et al, 2006), survivin-ΔEx3 may also be able to play a role via caspase-independent pathways.
These domains interact with various components of extracellular matrix (ECM), integrin and growth factors, which play critical roles in various physiological processes, including cell adhesion, migration, proliferation, differentiation, wound healing, fibrosis and hemostasis [ 13].
