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Caveolae and Cav-1 have emerged as novel targets in the control of various important cellular processes involved in the maintenance of cardiovascular homeostasis such as protein trafficking, lipid metabolism and signal transduction [11].
In agreement with transcriptome data [21], numerous and crucial P. carinii enzymes were identified for the metabolism of carbohydrate, energy, lipid, nucleotide, amino acids, glycans, cofactors, and vitamins, as well as for transcription, translation, cell cycle, DNA metabolism, and various important cellular processes.
As the PI3K/Akt/mTOR signaling pathway regulates various important cellular processes, it has become an most important therapeutic targets for anti-cancer drug development [ 9, 10, 25].
Thus, alternative splicing can play a major role in the activity of various important cellular mechanisms, such as cell differentiation, cell migration, cell growth and apoptosis.
This critical regulatory process is accomplished by activating the caspase cascade that results in the degradation of various important cellular proteins.
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ABC transporters are a large group of proteins which have roles in important cellular functions such as import and export of various substances including iron chelators (siderophores) [23].
Sirtuin 3 (Sirt3), a major mitochondrial NAD+-dependent deacetylase, targets various mitochondrial proteins for lysine deacetylation and regulates important cellular functions such as energy metabolism, aging, and stress response.
Mitochondria are very important cellular organelles, playing active roles in various functions, such as energy balance and cell cycle control.
By inactivating various tumour suppressor genes, this epigenetic modification can affect many important cellular processes, such as cell proliferation, apoptosis, invasion and metastasis.
Some homologues to S. cerevisae genes related to signalling modules and important cellular processes were found and distributed in various clusters.
The catalytic subunit of the NADPH oxidase (NOX) enzyme NOX2 is the most important cellular source of ROS, which are able to react with various molecules.
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CEO of Professional Science Editing for Scientists @ prosciediting.com