Sentence examples for various genetic mutations from inspiring English sources
Once libraries of tumors that mimic various genetic mutations are developed, clones from genetically distinct tumors can be isolated and co-transplanted into recipient zebrafish to recapitulate intratumoral heterogeneity and animals can be examined for the effects of drug treatment on clonal outgrowth and evolution.
Familial hypercholesterolemia (FH) is a hereditary condition caused by various genetic mutations that lead to significantly elevated low-density lipoprotein cholesterol levels and resulting in a 20-fold increased lifetime risk for premature cardiovascular disease.
Therefore, various genetic mutations are associated with specific hormone deficiencies.
52 Despite the discovery of various genetic mutations, the pathophysiology underpinning BrS remains elusive.
Previous studies have identified various genetic mutations in endometrial cancer, including PTEN, PIK3CA and KRAS.
The condition may be caused by various genetic mutations, exposure to teratogens such as retinoic acid, mechanical stress, or result from certain metabolic or haematologic disorders [ 4, 5].
Further, the diagnosis of primary haemochromatosis has improved since various associated genetic mutations were discovered some years ago.
In the pathogenesis of pancreatitis, various groups of genetic mutations may play an important role.
Meningiomas can arise spontaneously secondary to various genetic alterations with mutations on chromosome 22 being the most common [ 2].
Hence, it is necessary to seek various etiological factors, including genetic mutations that may be of importance in triggering recurrence and progression of acute to chronic pancreatitis.
Conventional approved antiviral drugs such as amantadine and oseltamivir [ 1] which are helpful to control the spread of influenza disease from the host cell [ 2] may not be suggested any longer due to various genetic drift and shift mutations which cause alterations in the antibody-targeted surface glycoproteins [ 3] and negative side effects and rapid emergence of resistant variants [ 4, 5].
