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Our microarray analysis revealed differential regulation of various genes which played an active role towards cell apoptosis and oncogenesis.
To halt cell division or trigger cell suicide, p53 needs to regulate the activity of various genes, which requires that it first bind to the DNA of the genes' regulatory sequences.
Previous studies have identified various genes which either directly contribute to virulence or act as virulence markers based on functional studies [12], [62], differential distribution between pathogenic and less or non-pathogenic strains [20], [63] or genome comparisons [19].
In this study, we suggest that disease severity by RDV strains is dependent on the difference in expression of various genes, which is in turn associated with RDV titer level and the variations in virus proteins among RDV strains.
Instead, this bacterium has acquired on a megaplasmid the various genes which allow it to metabolize arsenate.
In normal germ-line and somatic cells, DNA synthesis and cell division are tightly controlled by various genes, which help in the maintenance of genetic stability.
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This suggests differential regulation of the expression of various target genes which was confirmed by the detection of 431 differentially regulated genes immediately after hypoxia.
Cyst nematodes manipulate the expression of various plant genes which leads to the development of syncytia as their sole nutrient source [ 38].
Our analysis identified various interesting genes which encode cell adhesion molecules, ECM, extracellular matrix, lipid metabolism, CNS development, cell differentiation, transcription regulation, and invasion-related proteins.
Finally, activated Stat92E translocates into the nucleus and induces various target genes, which exert different effects on the cells, depending on the tissue or cell context, including proliferation, differentiation, migration, apoptosis, and cell survival [ 28].
For example, we know that all the "arian" traits that were the basis of the selection criteria of the Nazi doctrine do not actually correspond to real improvements by a gain of a new function, but all correspond to mutations causing losses of function in various pigment genes, which are all either recessive, or co-recessive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com