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Several illustrative examples showcasing the ease of converting deterministic codes to stochastic codes are provided.

In other words, these two cases should not be regarded as counterexamples of the substrate-envelope hypothesis but rather examples showcasing potential predictive powers of the hypothesis.

The aforementioned examples showcased in various publications include: 1) improved diagnosis, 2) scaling up of treatment, 3) elucidation of the development of drug resistance in unicellular organisms, 4) elucidation of human genetic variants that affect drug metabolism, and 5) development of genomic tools for population-level analysis of parasite and human [ 14, 36].

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Herein, after a brief introduction to the method of MD, we use a number of membrane transport proteins studied in our laboratory as examples to showcase the scope and applicability of the method and its power in characterizing molecular motions of various magnitudes and time scales that are involved in the function of this important class of membrane proteins.