Exact(5)
A stochastic model based on Gillespie's algorithm is derived which includes mutant species and employed to determine the sensitivity of HIV infection to different treatment strategies such as single therapy and combination therapy with various efficacy values.
The subsets of patients who received clobazam for a minimum of 1, 2, 3, 4, or 5 years were used for various efficacy and safety measures as indicated.
Prior to un-blinding the study data it is not possible to consider all possible adjustments needed to fully develop the appropriate model for determining changes in various efficacy parameters.
The combined approach of modeling both efficacy (ESSS) and safety (BMD) of GnRH modulation, as functions of E2, supported clinical trial designs with respect to treatment duration required to observe changes in various efficacy and bone-related biomarkers.
The manageable safety profile, lack of adverse pharmacokinetic interactions and apparent improvements in various efficacy parameters associated with the addition of ASA404 to carboplatin and paclitaxel support the initiation of a phase III trial of sufficient size to test this novel combination regimen with statistical power.
Similar(55)
Such discrepancy is due to the use of different formulations, as hydrochloride or sulfate salts are claimed to have various efficacies.
Since symptoms of scalp sensitivity are predominantly subjective, volunteers were asked to fill out questionnaires when stitches were removed to rate various efficacies and scalp compatibility statements.
In this respect, it can be speculated that depending on the epigenetic state of chromatin in the target locus, different functional domains fused to ZFs may exhibit various efficacies.
Clinical intervention trials using different agents in recent-onset type 1 diabetic patients have shown various efficacies (1– 7), which indeed highlights the complexity of translation from animal models to human type 1 diabetes.
Various secondary efficacy parameters supported these findings, and some of these have been republished separately for the evaluation of nasal obstruction [ 18] and eye symptoms [ 19].
Pyrroles are very common in naturally occurring porphyrins, alkaloids and co-enzymes possessing various pharmacological efficacies [58, 59, 60, 61].
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