Sentence examples for various effector molecules from inspiring English sources

a, Schematic diagram of mammalian CD8+ cytotoxic cells producing various effector molecules, such as PRF1 (perforin), GZM (granzymes), INF-γ (interferon-γ) and TNF-α (tumour necrosis factor-α).

The listed inducer cytokines activate key transcriptional regulators that define the multiple CD4+ lineages specialized for producing various effector molecules; genes not found in cartilaginous fishes are struck through.

Antibodies produced in response to a foreign antigen are characterized by polyclonality, not only in the diverse epitopes to which their variable domains bind but also in the various effector molecules to which their constant regions (Fc domains) engage.

These results demonstrate that memory CD8+ T cells localized in the same effector clusters are able to secrete various effector molecules according to their reactivating stimuli.

Here, we present novel data demonstrating that functionally active antigen-specific CTLs expressing various effector molecules also persist in patients treated for TB.

Binding of the growth factor results in kinase activation and consequently in the trans-phosphorylation of the receptor, as well as of various effector molecules resulting in the stimulation of a large number of signaling cascades.

They exhibit the ability to recruit diverse effector molecules thereby coordinating various membrane-mediated processes.

Macrophages respond to infection or injury by changing from a « resting » cellular phenotype to an « activated » state defined by the expression of various cytotoxic effector molecules.

In the same way, A20 depends on various adaptor and effector molecules to inhibit NF- κB, and thus functions differently depending on the cell type or received stimuli.

The most ancient defences of the living organisms are based on neuropeptide and protein hormone receptors, receptor kinases and PRR (mainly TLRs, lectin-like, NLRs and RIG-like families) able to signal the danger and increase the expression of various inflammatory and effector molecules [ 90- 92].

Inflammation, a complex process, is regulated by various immune cells and effector molecules, such as NO and proinflammatory cytokines.