Sentence examples for various downstream effectors from inspiring English sources

DAG and PA are two interconvertible lipids that influence membrane architecture and that act as essential signaling molecules that activate various downstream effectors, including master regulators of local protein synthesis and actin polymerization.

The receptor then typically activates a cascade of intracellular kinases, which then regulate various downstream effectors.

mTOR through various downstream effectors mediates a balance between cell growth and protein degradation.

Differential recruitment of these integrins may affect their signalling pathways by promoting or inhibiting the assembly of various downstream effectors.

There is evidence that CHK2 controls DNA repair; following activation by ATM, CHK2 phosphorylates various downstream effectors including BRCA1 (98).

In their active GTP-bound form, Rho GTPases interact with various downstream effectors to induce cellular responses.

As expected, phosphorylation levels of several downstream effectors of RAS were increased to various extents following RAS activation in HKe3 ER:HRASV12 cells.

(e) PTH binding activates PTH1R to stimulate several downstream effectors.

Our deterministic model offers insight into stimulus-response relationships between Epo and several downstream effectors.

Mutated KRAS transduces its oncogenic signal through several downstream effectors.

In fungi, several downstream effectors are targets of Tor signaling.