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Furthermore, the extensive distribution of the primary cellular receptor for Ad, the coxsackievirus and adenovirus receptor (CAR), allows adenoviral vectors to infect a broad range of host cells which may be disadvantageous in tissues with various different cell types, like the CNS.
As TRAIL is a potentially important cancer therapeutic, many laboratories have attempted to find sensitizing agents utilizing a wide range of chemical libraries against various different cell types.
Capsid mutants efficiently transducing various different cell types have been isolated from such libraries by biopanning on the cells of interest [14], [33], [34], [35], [36], [37].
Bone marrow is a complex tissue with various different cell types.
Whereas thymomas cannot be classified as benign or malignant at histopathology, thymic carcinomas are histopathologically malignant, occurring with various different cell types.
Both genes are upregulated under disease conditions in various different cell types in the brain, possibly to exert neuroprotective effects [ 49, 50].
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In practice, this means that integrating various different cell-level data will be effective in prediction, which includes proteomics, ionomics, phenotypic data of mutants, bioinformatics predictions, computational simulations of pathways, and molecular dynamics of biomolecules.
An array of various different adherent cell lines (human, mammalian, healthy and disease states) were grown on simple sterilised but otherwise untreated thin film surfaces as well as on electro-hydrodynamically patterned surfaces to produce topographically patterned culture surfaces.
A biological sample from a patient with an autoimmune disease typically contains various different immune cell subsets, and the process of microarray deconvolution can quantify their relative proportions.
In comparison to former liver transplantation trials we also have assessed markers that act on the various different inflammatory cells (neutrophils, macrophages, T-cells) and expanded our search pattern of inflammatory mediators to determine also molecules, not having been evaluated before.
The stimulation of various different immune cells is seen along with the indication of reproductive abnormality, which would reflect the problems seen with egg-laying upon IBV infection.
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