The migration and differentiation of the CNCC into cardiac ganglia are influenced by various developmental control genes.
To investigate the early phase of vertebrate evolution from a molecular perspective, the expression patterns of various developmental regulatory genes have been compared between the gnathostomes and the lamprey, one of the two extant groups of agnathans [ 4- 14].
To extend this analysis, we compared the 1393 genes whose predicted TSC is near (i.e., between -400 and +100) a putative MrpC binding site, to various lists of developmental genes.
In accordance with the analysis of GUS activity in these transgenic plants at various developmental stages, these homologous genes had distinct expression patterns.
Other interesting highly down regulated genes of various functions include the developmental genes: MEST (the most down regulated in large follicles, 28-fold), IHH (also Figure 5B) and MYC, and also JAKMIP1, which participates in cell polarisation.
A wide range of gene expression profiles based on organs and tissues at various developmental stages identified organ/tissue specific genes as well as growth stage-specific genes.
Among the disease down-regulated genes, a significant number of genes associated to various developmental processes were identified and included a relatively high proportion of genes linked with auxin and cytokinin signalling pathways, suggesting that normal developmental processes are strongly affected in wilting plants (Figure 3D).
The use of testes at various developmental stages highlighted several gene activation or repression patterns throughout the reproductive cycle.
More intriguingly, there are numerous examples suggesting the implication of TEs in the normal epigenetic regulation of genes, including genes involved in various developmental processes [ 68, 109, 136].
