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To the Editor: Delhi, in the northern part of India, has had outbreaks of dengue caused by various dengue virus types in 1967, 1970 , 1982 1988, and 1996 (1 – 5 ).
22 Differences at serotype and molecular level are important not only for dengue endemic countries but for physicians in non-endemic countries in their management of febrile returned travelers infected with various dengue viruses circulating globally.
In the next two studies, the authors managed to apply new lectins, CramoLL from Cratylia mollis 847) and BmoLL from Bauhinia monandra, in the detection of various dengue sera serotypes applicable in the analysis of an early stage of dengue virus infection.
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In China, although sporadic cases have been reported in various regions, dengue outbreaks have been traditionally confined to southern coastal regions, including Hainan, Fujian, Guangdong and Guangxi provinces, where hot and humid weather provides an ideal environment for mosquito breeding and the transmission of DENV.
The possible beneficial effects of corticosteroids on the various manifestations of dengue infection need evaluation by adequately powered, well designed, randomised controlled trials.
Subsequently, we expanded this noninvasive diagnostic tool to screen for various infections, including dengue, at entry borders.
We highlight three patients who were admitted to our unit in various stages of dengue infection and developed DSS.
Several other official reports described outbreaks of dengue in various localities of Yemen (unpublished data, Ministry of Health, Yemen).
48, 49 During the last decade, several studies have addressed the economic burden of dengue in various settings.
To shed further light on the complex interplay among the various factors that affect dengue transmission, studies are being conducted on complete genome sequences of dengue viruses, vectorial capacity of local Aedes spp. mosquitoes, and cross-reactive immune responses to different dengue serotypes.
Research efforts to prevent and treat dengue include various means of vector control, vaccine development, and antiviral drugs.
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