SEM examination of biofilms cultivated in the CBD revealed that different bacterial strains adopted various structural conformations that were distinct from the "stalk" and "mushroom cap" biofilms formed in flow cells by P. aeruginosa.
There is evidence that plaques can be induced by a seeding agent [ 22] and so it may be that pre-existing plaques produce seeds via diffusion or degradation processes, which induce the formation of neighboring plaques or represent a 'pool' of various Aβ conformations that further contribute to local toxicity and facilitate plaque formation [ 8, 11, 15, 18, 23].
Comparative analysis of various conformations indicated that there is uniform penetration of the inner tail tube into the E. coli periplasm and a significant movement of the baseplate away from the outer membrane during tail contraction.
Furthermore, according to earlier circular dichroism data, the C1b domain can adopt various ligand-dependent stable conformations that affect the catalysis rate by changing the structural conformation of the C1a C2a catalytic core [ 48].
Of relevance to these issues are studies that describe various conformations of Ado· that may be important to catalysis as well as the roles of nearby amino acids with which it may interact.
The dependence of the large conformational transitions and rearrangements on specific structural elements with identified mechanistic contributions suggests the possibility of various intermediate and functionally-specialized molecular conformations that can be adopted by individual members of the NSS family of transporter proteins.
Sup35p fibers adopt various conformations in vitro that trigger the formation of phenotypically distinct [PSI+] cells upon transformation into [psi−] cells [53] [55].
The decomposition of the landscape in sub-states allows identification of the conformations that have features relevant to the transition state, and therefore, allows identification of the subtle changes in various dynamically relevant residues.
Also, the NMR ensemble may not include every naturally occurring conformation, as it itself rather represents one of the sets of conformations that fit the experimental data.
To dispel this confusion LIFE here adduces a rule-of-thumb from the anthropometric conformations that distinguish friendly Chinese from enemy alien Japs.
