Sentence examples for various cellular pathways from inspiring English sources
Instead, significantly improved outcomes likely require synergistic therapies that target various cellular pathways.
The maintenance of pluripotency of CSCs under various pathophysiological conditions requires a complex interaction between various cellular pathways including those involved in homeostasis and energy metabolism.
This chapter introduces the use of selective Histone acetyltransferases (HATs) inhibitors as mechanistic tools to probe the catalytic features of HATs and their roles in various cellular pathways.
RNA immunoprecipitation with the known stress granule aggregates TIAR and G3BP1 was performed on astrocytoma cells, and subsequent analysis revealed that astrocytoma stress granules harbor unique mRNAs for various cellular pathways, including cellular migration, metabolism, translation, and transcriptional regulation.
Elucidating what effect the silencing of SUMO2/3 expression has on gene expression will help to identify the impact of SUMO2/3 conjugation on the various cellular pathways.
Tankyrases are ADP-ribosyltransferases that play key roles in various cellular pathways, including the regulation of cell proliferation, and thus they are promising drug targets for the treatment of cancer [12].
The molecular basis of PTH-induced calcification was studied in various tissues, and several cellular pathways, especially the tumour necrosis factor family pathway.
The cytotoxic effect of mHtt takes various forms that affect several cellular pathways and functions.
Oncogenic transformation of a normal cell is a multistep process that requires activation or inactivation, usually by mutagenic events, of several key genes controlling various essential cellular pathways that are involved in growth and development.
We describe that these alterations can be achieved by changing: (i) the nature and structure of the DNA lesion induced; (ii) conformational alterations induced in DNA by these lesions; and (iii) various cellular signaling pathways initiated by platinum-DNA damage.
These small GTPases regulate various cellular signaling pathways [8], [9].
