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The dual miRNA-1 imaging systems, which provides the complementary imaging information about miRNA biogenesis, could be useful to sense miRNA expression during various biologic processes.
Because protein sumoylation is known to be involved in the regulation of various biologic processes, the massive post-ischemic increase in protein sumoylation may play a critical role in defining the final outcome of neurons exposed to transient ischemia.
Although PI3K has been the focus of intense study in various biologic processes including apoptosis, metastasis, and neuronal differentiation, it is only recently that the focus has shifted to understanding the role of PI3K in cardiac function, hypertrophy, and heart failure.
Growing evidence suggests that miRNAs play an important role in various biologic processes, including cell proliferation, development, and differentiation [ 4, 5].
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Reporter genes have been used as molecular-genetic imaging agents for monitoring various cellular biologic processes [33 35].
Oxidative stress initiates complex biologic processes in various layers of the skin, which can result in transient or permanent genetic damage, activation of transcription factors, such as Ap1 and NF-κB, and signaling pathways, such as the ERK, JNK, and p38 MAPK pathways, involved in cell growth and differentiation and in degradation of the connective tissue of the dermis.
The function of these highly dynamic raft domains as physical platforms for various molecules is involved in a variety of biologic processes by serving as organizing centers for the assembly of signaling molecules into functional complexes [ 4, 5].
However, more recent studies using genetic deletion approaches and the recent development of isoform-specific PI3K inhibitors have revealed highly specific functions of the different isoforms in certain biologic processes, promising novel therapeutic strategies for various disease states (2, 4).
The temporal relationships between ontologies that are associated with various biologic, metabolic, and regulatory pathways were identified and related to developmental processes associated with skeletogenesis, vasculogenesis, and neurogenesis.
Ovarian cancer-induced altered biologic processes are expressed as aberrant molecules that belong to various biochemical families, such as DNA, mRNA, proteins (and related subfamilies as glycosylated proteins, peptides, and autoantibodies), and metabolites.
A biologic medical product (biological or biologic) is a medicinal product that is produced by biologic processes rather than chemical synthesis.
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