We examined high-impact journal publications from 2001 to 2010 and extracted data covering authors, institutions, simulation modality, purposes of simulation, and various aspects of study design/methodology used.
There are various aspects of study design and implementation that can affect the validity of test accuracy studies [ 39].
The potential risk of bias associated with various aspects of study design is described in Additional File 4, Table S2.
Because the capability to search the phylesystem repository is required for various use cases (e.g. various aspects of study curation), we implemented an additional tool called OTI (which stands for 'open tree indexer') which parses otNexSON documents and indexes their contents to enable fast searches across studies and their included elements (e.g. trees).
This chapter discusses the various aspects of hazard studies that have a bearing on the development and specification of safety instrumented systems (SISs).
Arabidopsis thaliana has been widely used as a model system, in various aspects of biological studies, such as genomics, genetics, cellular, developmental and molecular biology.
To date, numerous transgenic fish lines that express engineered versions of Gal4 in specific cells, organs, and tissues have been generated and used for various aspects of biological studies.
We also thank Tom Laudemann, Jim Roberts, and Shuran Li for their help with various aspects of these studies.
The authors also thank Joel Colvill for performing the analytical assays, Dr. Andrew Wallace, Justine Rivett and Alexis Poole for their assistance with various aspects of the studies.
MF, CPM, EP, EM, MP, SM, SB, SR and JRH have been engaged by FAES FARMA S.A. as experts for various aspects of the studies (PET technique, pharmacokinetic and statistical methods).
