Sentence examples for various apoptotic pathways from inspiring English sources

D3.4 therefore is an excellent tool to define the precise role of caspase-3 in the various apoptotic pathways.

These results indicate that photodynamic TiO2 Ws could load GA to induce a marked improvement in antitumor activity in various apoptotic pathways.

Further research for therapeutic interventions is warranted in several areas such as binding and elimination of endotoxin by extracting the source of sepsis, blocking of various apoptotic pathways, or even extracorporeal removal of circulating toxic mediators using high volume hemofiltration, high permeability hemofiltration and plasma filtration coupled with adsorption [85].

Activation of caspase family members is at the core of apoptosis, representing a point of intersection of various apoptotic pathways in various types of cancer cells, including prostate cancer cells.

In addition, we explored whether this newly characterized necrotic signal shared common signaling hubs with various apoptotic pathways by examining the cytotoxic action of MPA on different tumor cells exhibiting resistance to apoptosis.

To further study the molecular mechanisms underlying the CA-Akt-mediated altered chemosensitivity, we analysed various apoptotic pathways.

As caspases are known to have pivotal roles in various apoptotic signaling pathways, we measured activities of initiator caspases (caspase-8 and caspase-9) and effector caspase (caspase-3) in STS-treated cells using the colorimetric assay kits.

However, although the knowledge on the various apoptotic receptors and pathways involved in sensitivity or resistance of OC to chemotherapy has increased significantly in the last two decades, this issue is still in permanent upgrade.

PI3K/PKB activates various anti-apoptotic pathways, whereas mTOR (a downstream effector of PI3K/PKB) regulates cell cycle transition.

Recently, mounting evidences suggest that cancer cells can commit to death by various non-apoptotic pathways such as autophagy, mitotic catastrophe and accelerated senescence.

It is likely that these conflicting results arise because of different interactions between the various treatment modalities and apoptotic pathways.