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Secondly, this method is generalizable, opening the door for deep sequencing-based mutational screening on a variety of sequencing platforms.
"No one has ever put together a data processing center this size for sequencing because no one has ever been able to sequence this many genomes," says Reid. Complete Genomics will focus entirely on human-genome sequencing, unlike other companies, which use their technology for a variety of sequencing projects.
We further show that DeepVariant can learn to call variants in a variety of sequencing technologies and experimental designs, including deep whole genomes from 10X Genomics and Ion Ampliseq exomes, highlighting the benefits of using more automated and generalizable techniques for variant calling.
NGS is something of a catch-all term describing a variety of sequencing technologies that have largely replaced Sanger sequencing.
Nowadays, we have a surprising variety of sequencing technologies, each with its own strengths and weaknesses.
Illumina has a variety of sequencing instruments dedicated to different applications.
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DNA is composed of millions of these bases strung in an apparently limitless variety of sequences.
Hernández-Triana, L. M. et al. Recovery of DNA barcodes from blackfly museum specimens (Diptera: Simuliidae) using primer sets that target a variety of sequence lengths.
I advocate testing current algorithms on a wider variety of sequences to determine their limits of applicability.
One of the evolved clones, GinL7C7, catalyzed efficient, site-specific recombination in a variety of sequence contexts.
The final 80-minute version is full of "peaks and troughs" offering a variety of sequences that play with audiences by "raising their expectations and heartbeats, then letting them think and catch up with you".
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