In this population, the tamoxifen benefit varied by Recurrence Score and was greatest for those with low Recurrence Score values.
The gap time model requires the same assumptions as the Cox proportional hazards model, but they allow the baseline hazard to vary from recurrence to recurrence.
This model requires the same assumptions as the Cox model, but, unlike the AG model, it allows the baseline hazard to vary from recurrence to recurrence, the hazard function for the j t h event for the i t h subject is: h ij (t ) = h 0 j (t ) exp (β j ′ Z i (t ) ).
"The basic conclusion, then, appears to be that big tsunamis vary in recurrence [time], from only 60 years to about 2000 years," Sieh writes in an e-mail.
Here, we briefly demonstrate some evolutionary stages of the "toroidal" dynamics in the model as gK1 is varied using 1D recurrence maps.
At the practitioner level, short-term risks of recurrence varied widely, from <10% risk among low-risk doctors to >80% risk among high-risk doctors.
Short-term risks of recurrence varied significantly among doctors: there was a strong dose-response relationship with number of previous complaints and significant differences by doctor specialty and sex.
In group B serum PSA level ranged from 0.4 to 1.4 ng/mL and the maximal transverse dimension of a suspect local recurrence varied from 5.0 to 7.2 mm.
The median survival from recurrence varied depending on disease subset, with patients with luminal A at 39.6 months, luminal B at 27.4 months, HER2+/ER- at 20.9 months, and triple-negative tumors at 15.5 months (p = 0.0246, Figure 1a).
The prognostic value of tumour histological grade and hormone receptors status varied as distant recurrence-free interval (DRFI) increased.
