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Yet the subset of P450 genes that have previously been implicated in insecticide resistance in An gambiae, show a surprisingly varied profile of tissue enrichment, confirmed by qPCR and, for three candidates, by immunostaining.
To date, no single explanation has been able to account for the broad and varied profile of these deficits [ 136].
Consistent with complex inheritance, this small subset of patients with severe IBD exhibit a varied profile of mutation with limited sharing of specific variants across the set of eight exomes.
Idiopathic Parkinson's disease is characterized by progressive brain pathology affecting multiple neurotransmitter systems, leading to a dynamic and varied profile of physical, motor, cognitive and psychiatric dysfunction (Kehagia et al., 2010 a ).
Further investigation focusing on the expression of their corresponding proteins in paraffin embedded sections from 38 chronic hepatitis C patients (14 cases with F0 or F1, 6 cases with F2 and 18 cases with F3 or F4) resulted in varied profile.
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Thus, the "real" cancer gene expression signals may be buried in these highly varied profiles.
In an earlier study, Li et al. [ 54] speculated that there may be many genes with variable expression between individual tumor cells making the differentially expressed genes that are really tumor-specific hard to find in the highly varied profiles.
GBMs notorious for their antigenic heterogeneity often express varied antigen profile within single tumors and between patients [ 43, 44].
Vincentric used varied insurance profiles (new drivers, less experienced drivers and experienced drivers) to determine the value for each vehicle.
Pulmonary thromboembolism (PTE) is a dangerous complication of traumatic injury, with varied risk profiles and treatment options.
Critical and normal depths are important for computing gradually varied flow profiles and for the design, operation, and maintenance of open channels.
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